The U.S. Food and Drug Administration (FDA) has issued warning letters to six companies selling unapproved seizure drugs for dogs and cats. These products, which claim to treat and control seizures, are not FDA-approved and have not undergone the necessary review process to ensure their safety, efficacy, or proper manufacturing standards.

The following companies have received warning letters:

1. Nutrition Strength Ltd. EOOD (Dog Seizure and Epilepsy Supplement, Blood Support for Dogs)

2. Evolution Pets (SeizureGuard Plus, Life Span Arthritis & Mobility Advanced Enzyme Therapy)

3. Doc Ackerman's Pet Products (Doc Ackerman's - Epilepsy & Seizure Formula)

4. Energetic Essences, LLC dba Pet Essences (Seizures Formula)

5. HD Frenchies, LLC/Bully Baum (Bully Baum No Seize, Can-B-Gone - Cancer Oil Extract, Brain & Neurological)

6. Vet Select Formula, Inc. (Vet Select Nuroplex Capsules, Vet Select Nuroplex© - 2oz Homeopathic Spray)

These products were sold on the companies' websites, social media platforms, and Amazon stores without a prescription or veterinary oversight. Since they have not been approved by the FDA, these drugs have not been verified for safety or effectiveness, which means their potential risks to animals and humans are unknown.

Seizure disorders in animals can have various causes, including genetic conditions, trauma, liver disease, diabetes, cancer, or exposure to toxins. Among these, idiopathic epilepsy is one of the most common seizure disorders in dogs, affecting an estimated 1% to 5% of dogs. The FDA has conditionally approved two drugs—including KBroVet-CA1 —to treat this serious condition. KBroVet®–CA1 was the first drug conditionally approved by the FDA for the control of seizures associated with idiopathic epilepsy in dogs. It works by providing a consistent and reliable source of potassium bromide, and is a well-known choice to help control seizures associated with IE in dogs.

However, these treatments should only be used under the supervision of a licensed veterinarian, as they require proper diagnosis and management to ensure the health and safety of the animal.

Pet owners who have been using the unapproved products mentioned in the warning letters are advised to consult a licensed veterinarian for proper diagnosis and treatment. Any remaining products should be disposed of safely. Additionally, adverse reactions to animal drugs should be reported to the FDA's Center for Veterinary Medicine.

The FDA has instructed the companies to respond within 15 days to outline how they will address the violations. If these issues are not rectified, the FDA may take further legal action, including product seizures or court orders to cease the sale and distribution of the unapproved products.

The FDA will continue to monitor the market to protect both animal and human health, taking necessary steps to address the risks posed by unapproved drugs.