A study compared the characteristics of recovery from isoflurane anesthesia in healthy non premedicated dogs after anesthetic induction by IV administration of tiletamine-zolazepam with those observed after induction by IV administration of alfaxalone, ketamine-diazepam, or propofol.

Six dogs were given four different anesthetic treatments.   Anesthesia was induced by IV administration of the assigned induction drug or combination and maintained with isoflurane in oxygen for 60 minutes. Most cardiorespiratory variables, body temperature, and time to extubation did not differ between tiletamine-zolazepam and other induction treatments. Recovery was better with propofol or alfaxalone than with tiletamine-zolazepam but did not differ between tiletamine-zolazepam and ketamine-diazepam treatments.

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Recovery characteristics of dogs following anesthesia induced with tiletamine-zolazepam, alfaxalone, ketamine-diazepam, or propofol and maintained with isoflurane.